Choupo-Moting’s goal gave Stoke an early lead.
Paul Pogba headed towards goal from a corner and the ball was inadvertently directed into the net off the back of Marcus Rashford’s head.
Romelu Lukaku put the Red Devils in front shortly after the break but Choupo-Moting levelled in the 63rd minute, heading in Xherdan Shaqiri’s corner at the back post.
As both sides pushed for a winner, Lukaku wasted an excellent chance in the 81st minute when he fired over from Antonio Valencia’s cross after losing his marker eight yards out.
Watch highlights and goal moments below: